主持科研项目 1)国家自然科学基金,82001803,慢性失眠障碍伴发抑郁的个体化脑网络机制及早期预测研究,2021/01-2023/12,24万元,在研,主持 2)四川省科技厅应⽤基础研究计划,2020YJ0197,基于影像遗传策略探讨慢性失眠伴抑郁的多模态脑⽹络机制,2020/1-2021/12,10万,在研,主持 3)成都市卫健委医学课题,2019115,基于神经影像结合机器学习技术对失眠伴情绪障碍的识别,2020/1-2021/12,2万(自筹),在研,主持 发表文章30余篇,其中SCI论文17篇,发表的第一作者及通讯作者论文包括: [1] L. Gong, Xu, R., Qin, M., Liu, D., Zhang, B., Bi, Y. and Xi, C. New potential stimulation targets for noninvasive brain stimulation treatment of chronic insomnia. Sleep Medicine 75 (2020) 380-387.. [2] L. Gong, R. Xu, D. Liu, C. Zhang, Q. Huang, B. Zhang, and C. Xi, Abnormal functional connectivity density in patients with major depressive disorder with comorbid insomnia. Journal of Affective Disorders 266 (2020) 417-423.. [3] L. Gong, R. Xu, D. Liu, L. Lan, B. Zhang, and C. Zhang, The specific impact of apolipoprotein E epsilon 2 on cognition and brain in healthy elder and mild cognitive impairment. Frontiers in Aging Neuroscience 11 (2019) 374.. [4] L. Gong, R. Xu, L. Lan, D. Liu, J. Shen, B. Zhang, and A.s.D.N. Initiative, The CD33 genotype associated cognitive performance was bidirectionally modulated by intrinsic functional connectivity in the Alzheimer’s disease spectrum. Biomedicine & Pharmacotherapy 115 (2019) 108903.. [5] L. Gong, T. Liao, D. Liu, Q. Luo, R. Xu, Q. Huang, B. Zhang, F. Feng, and C. Zhang, Amygdala Changes in Chronic Insomnia and Their Association with Sleep and Anxiety Symptoms: Insight from Shape Analysis. Neural Plasticity 2019 (2019).. [6] L. Gong, H. Li, D. Yang, Y. Peng, D. Liu, M. Zhong, B. Zhang, R. Xu, and J. Kang, Striatum Shape Hypertrophy in Early Stage Parkinson's Disease With Excessive Daytime Sleepiness. Frontiers in neuroscience 13 (2019) 1353.. [7] L. Gong, Y. Yin, C. He, Q. Ye, F. Bai, Y. Yuan, H. Zhang, L. Lv, H. Zhang, and C. Xie, Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research 84 (2017) 9-17.. [8] L. Gong, H. Shu, C. He, Q. Ye, F. Bai, C. Xie, and Z. Zhang, Convergent and divergent effects of apolipoprotein E epsilon4 and epsilon2 alleles on amygdala functional networks in nondemented older adults. Neurobiol Aging 54 (2017) 31-39.. [9] L. Gong, C. He, Y. Yin, Q. Ye, F. Bai, Y. Yuan, H. Zhang, L. Lv, Z. Zhang, and C. Xie, Nonlinear modulation of interacting between COMT and depression on brain function. European Psychiatry 45 (2017) 6-13.. [10] L. Gong, C. He, Y. Yin, H. Wang, Q. Ye, F. Bai, Y. Yuan, H. Zhang, L. Lv, and H. Zhang, Mediating role of the reward network in the relationship between the dopamine multilocus genetic profile and depression. Frontiers in Molecular Neuroscience 10 (2017) 292. |